Study: The Effects of the Timing of Tranexamic Acid Administration on Blood Loss in Hip Fractures

Link to study information: https://clinicaltrials.gov/ct2/show/NCT04488367

Country: USA

Start date: 2020-07-06

Abstract: The study aims to initiate TXA administration immediately upon diagnosis of hip fracture in the Emergency Department. This will be a single blind randomized controlled trial comparing early administration of TXA in the ED in addition to perioperative dosing versus the standard perioperative administration only. The study population will include patients who have sustained a femoral neck, intertrochanteric, or subtrochanteric femur fracture and are undergoing surgical internal fixation or arthroplasty. We will prospectively compare the need for blood transfusion, total and hidden blood loss, postoperative complications, length of stay and readmission within 30 days.